7-Amino-benzocycloheptenes
US4091115A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 26, 1976 |
| Grant date | May 23, 1978 |
| Priority date | — |
| Expiry date | Jul 26, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2602/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel 7-amino-benzocycloheptenes of the formula ##STR1## wherein X is selected from the group consisting of hydrogen, chlorine, bromine and iodine in the 2- or 4-position when a halogen, Y and Z are hydrogen or together form a double bond, R is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms and phenyl optionally substituted with fluorine, chlorine, methyl or methoxy, R.sub.1 is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms and alkenyl of 2 to 5 carbon atoms and R.sub.2 is selected from the group consisting of alkyl of 1 to 5 carbon atoms and alkenyl of 2 to 5 carbon atoms and R.sub.1 and R.sub.2 taken together with the nitrogen atom to which they are attached form a saturated heterocycle of 4 to 6 carbon atoms and optionally containing another hetero-atom and optionally substituted with an alkyl of 1 to 5 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts having antidepressive activity and their preparation and novel intermediates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.