Patent · US Expired

Theophylline salts of 5-methylisoxazole-3-carboxylic acid

US4092417A · kind A · utility

7Cited by

3References

37Claims

0Family size

Assignee

Johann A. Wulfing · DE

Inventors

Karl Credner
Joachim Goring · Gronau, DE
Gunter Brenner
Manfred Tauscher · Gronau, DE

Key dates

Filing date	Dec 8, 1976
Grant date	May 30, 1978
Priority date	—
Expiry date	Dec 8, 1996

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D261/18
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The salts of N-unsubstituted, N-monosubstituted and N,N-disubstituted 7-(3-amino-2-hydroxypropyl)theophylline and 5-methylisoxazole-3-carboxylic acid are hypolipidaemic agents. The compounds, of which the 7-[3-(N-methyl-N-2-hydroxyethyl)amino-2-hydroxypropyl]-theophylline salt of 5-methylisoxazole-3-carboxylic acid is a representative embodiment, are prepared by allowing the isoxazole acid and the amine to react.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.