Process for preparing monomer of bile acid sequestrant polymer
US4093657A · kind A · utility
1Cited by
2References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 9, 1976 |
| Grant date | Jun 6, 1978 |
| Priority date | — |
| Expiry date | Apr 9, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C209/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention disclosed herein relates to a novel process for preparing the monomer, 3-[N-(3-chloropropyl)methylamino]-N,N,N-trimethyl-propan-1-aminium chlorid e, which comprises reacting N,N-bis(3-chloropropyl)methylamine with trimethylamine. The 3,3-ionene monomer thus obtained is a key intermediate for making the linear, unbranched, non-cross-linked polymer, poly-[{methyl-(3-trimethylammoniopropyl)imino}trimethylene dichloride], which is valuable as an oral bile acid sequestrant.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.