9.beta.-D-Arabinofuranosylpurine nucleotides and method of use
US4093714A · kind A · utility
35Cited by
9References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 15, 1974 |
| Grant date | Jun 6, 1978 |
| Priority date | — |
| Expiry date | Mar 15, 1994 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/20
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
9-.beta.-D-Arabinofuranosyl nucleotides of the following structure are disclosed: ##STR1## wherein AP is a 3' or 5' phosphorylated arabinofuranoside or the corresponding 3', 5' cyclic phosphate joined by a glycoside linkage to N.sup.9 of the aglycon component of said nucleotide, and Z is H, C.sub.1 -C.sub.6 alkyl, C.sub.7 -C.sub.10 aralkoxy, or hydroxy. Compounds prepared according to the invention exhibit antiviral activity in vitro, while others are precursors useful in the synthesis of bioactive compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.