Patent · US Expired

Non-amphetaminic psychostimulating compositions of 1,4-disubstituted piperazines

US4096259A · kind A · utility

4Cited by
3References
4Claims
0Family size

Inventors

Key dates

Filing dateMay 10, 1976
Grant dateJun 20, 1978
Priority date—
Expiry dateMay 10, 1996

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D295/15
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

1,4-DISUBSTITUTED PIPERAZINE DERIVATIVES HAVING THE FORMULA ##STR1## wherein R is C.sub.1-3 alkyl, halogen or hydrogen; R.sub.1 is phenyl or C.sub.1-3 alkyl; R' is hydrogen when R.sub.1 is alkyl and is the same as R when R.sub.1 is phenyl; R.sub.2 is hydrogen or C.sub.1-3 alkyl; n is 2-4; n' is 1-4; and A is a group comprising a trivalent organic function which may be acid, ester, nitrile or amide, in which latter case the nitrogen of the amide is part of the ring, and more particularly COOH, COONa, COOCH.sub.3 or COOC.sub.2 H.sub.5. These derivatives or their addition salts with pharmaceutically acceptable acids, have high psychostimulating activity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.