Process for the preparation of pyroglutamyl-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn
US4098777A · kind A · utility
6Cited by
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8Claims
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Assignee
Inventors
Key dates
| Filing date | Mar 14, 1977 |
| Grant date | Jul 4, 1978 |
| Priority date | — |
| Expiry date | Mar 14, 1997 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/28
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention is directed to the chemical process for the preparation of the polypeptide, pyroglutamyl-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn and to intermediates in said process. The polypeptide prepared by the present process is useful in the treatment of autoimmune diseases such as Lupus like pathology and specifically for the treatment of Lupus Erythematosus in man. This polypeptide is also useful for selectively stimulating T-cell activity in aging subjects.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.