Patent · US Expired

Process for the preparation of 4-androstene-3,17-dione derivatives

US4100027A · kind A · utility

5Cited by

3References

10Claims

0Family size

Assignee

SCHERING CORPORATION · US

Inventors

Alfred Weber · Wien, AT
Mario Kennecke · Berlin, DE
Rudolf Mueller · Lake Forest, US
Ulrich Eder · Berlin, DE
Rudolf Wiechert · Berlin, DE

Key dates

Filing date	Dec 16, 1976
Grant date	Jul 11, 1978
Priority date	—
Expiry date	Dec 16, 1996

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10S435/872
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

A process for the preparation of 4-androstene-3,17-dione derivatives of the formula ##STR1## wherein X is 6,7-methylene or fluoro, chloro, or methyl in the 6- or 7-position, comprises fermenting a sterol of the formula ##STR2## wherein X is as above and R.sub.1 is a hydrocarbon residue of 8-10 carbon atoms with a microorganism culture capable of degrading the side chain of a sterol.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.