2-[N-phenyl-N-(cycloalkyl-methyl)-amino]-2-imidazolines and salts thereof

US4100292A · kind A · utility

Assignee

• Boehringer Ingelheim GmbH · DE

Inventors

• Helmut Stahle
• Herbert Koppe · Ingelheim am Rhein, DE
• Werner Kummer · Ingelheim am Rhein, DE
• Klaus Stockhaus
• Wolfgang Hoefke · Wiesbaden, DE
• Franz Josef Kohn · Bingen, DE

Key dates

• Filing date: Aug 12, 1977
• Grant date: Jul 11, 1978
• Expiry date: Aug 12, 1997

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds of the formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3, which may be identical or different from each other, are each hydrogen, fluorine, chlorine, bromine, methyl, ethyl, methoxy, hydroxyl, trifluoromethyl or cyano; and PA1 R.sub.4 is (cycloalkyl of 3 to 6 carbon atoms)-methyl; and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as analgesics.