3,4-Dihydro-2-methyl-4-oxo-2H-1,2-benzothiazine-3-carboxylic acid-1,1-dioxide
US4100347A · kind A · utility
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4References
1Claims
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Key dates
| Filing date | Jun 10, 1976 |
| Grant date | Jul 11, 1978 |
| Priority date | — |
| Expiry date | Jun 10, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D279/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Process for production of 3,4-dihydro-2-methyl-4-oxo-2H-1,2-benzothiazine-3-carboxylic acid-1,1-dioxide by hydrolysis, in the presence of hydroxide ions, of an alkyl or aralkyl ester thereof followed by precipitation of the acid at pH below 6.0 and its use as an intermediate for the production of N-(2-pyridyl)-3,4-dihydro-2-methyl-4-oxo-2H-1,2-benzothiazine-3-carboxamid e-1,1-dioxide and the analogous N-(2-thiazolyl)-compound, effective antiinflammatory agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.