Method for inhibiting emesis and compositions therefor
US4101662A · kind A · utility
7Cited by
3References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 3, 1973 |
| Grant date | Jul 18, 1978 |
| Priority date | — |
| Expiry date | May 3, 1993 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D211/32
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
1,4-(3-)Disubstituted piperidines are disclosed which have useful antiemetic properties. The compounds have the general formula: ##STR1## wherein R is halogen, R.sup.1 is hydrogen and halogen, n is a positive integer from 2-4 and A is --C(O)-- and --CHOH--. The pharmaceutically acceptable acid addition salts of the basic compounds are particularly useful as antiemetics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.