Process for producing human lysozyme
US4104125A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 13, 1977 |
| Grant date | Aug 1, 1978 |
| Priority date | — |
| Expiry date | Jul 13, 1997 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/831
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
It has been discovered that lysozyme in the blood is concentrated into the albumin fraction when the blood is fractionated by the alcohol fractionation method at lowered temperature or the ammonium sulfate fractionation method. Lysozyme can be produced by contacting the albumin fraction with a weakly acidic cation-exchanger such as CM-cellulose to adsorb selectively the lysozyme with the cation-exchanger and then eluting the lysozyme adsorbed from the cation-exchanger.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.