1-Substituted-2-(2-pyridinyl)ethanone N-oxides
US4104274A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 16, 1977 |
| Grant date | Aug 1, 1978 |
| Priority date | — |
| Expiry date | Aug 16, 1997 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D213/89
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
1-Substituted-2-(2-pyridinyl)ethanone N-oxides having the formula I or II: ##STR1## wherein R.sub.1 is hydrogen or lower alkyl; R.sub.2 and R.sub.3 are each hydrogen, halogen, hydroxy, lower alkyl, lower alkoxy, or benzyloxy; R.sub.4 is halogen, hydroxy, lower alkyl, lower alkoxy, benzyloxy, ortho-amino, ortho-lower alkylamino, ortho-alkanoylamino or ortho benzoylamino; and R.sub.5 is hydrogen, halogen, hydroxy, lower alkyl, lower alkoxy or benzyloxy; the pharmaceutically acceptable acid addition salts thereof, and a process for the preparation thereof, are described. The compounds of this invention are useful for the treatment of allergic conditions and for the treatment of hyperacidity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.