.alpha.-Amino ketone derivatives
US4105790A · kind A · utility
22Cited by
1References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 9, 1976 |
| Grant date | Aug 8, 1978 |
| Priority date | — |
| Expiry date | Nov 9, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D295/185
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention concerns .alpha.-aminoacyl derivatives of phenyl-, phenoxy-, thiophenoxy- and phenylsulphinylalkanoic acids together with their amides, esters and pharmaceutically acceptable salts; processes for their preparation; and pharmaceutical compositions for therapeutic use in inhibiting the formation of thrombi and also in reducing the persistence of thrombi formed in the blood of warm blooded animals. Representative compounds of the invention are methyl 4-(aminoacetyl)phenoxyacetate, 4-(aminoacetyl)phenoxyacetic acid and methyl 4-(aminoacetyl)-thiophenoxyacetate, preferably as their hydrochlorides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.