Method for optical resolution of DL-lysine compounds
US4108723A · kind A · utility
3Cited by
2References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 1, 1977 |
| Grant date | Aug 22, 1978 |
| Priority date | — |
| Expiry date | Sep 1, 1997 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P13/08
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method for optical resolution of DL-lysine alkyl ester or acid-addition salts thereof by contacting an aqueous solution of the ester or salts thereof with a non-specific protease obtained by culturing bacteria belonging to the genus Streptomyces, e.g. St. griseus, at weakly acidic pH and a temperature not exceeding 60.degree. C until 60 - 90% by weight of L-lysine ester or acid-addition salts thereof takes part in a reaction, and recovering L-lysine or acid-addition salts thereof thus produced by a conventional manner. The protease may be immobilized on an insoluble carrier in advance.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.