Pharmaceutical, compositions containing substituted 4'-hydroxyphenyl guanidines and methods of using same
US4109014A · kind A · utility
46Cited by
0References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 25, 1977 |
| Grant date | Aug 22, 1978 |
| Priority date | — |
| Expiry date | Jan 25, 1997 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/155
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel aromatic guanidine compounds having the formula: ##STR1## wherein: R.sub.1 is hydroxyl, methyl or hydroxymethyl and R.sub.2 is hydrogen or methyl, are found to have biological activity. The guanidine compounds and their salts are shown to be active as vasoconstrictor agents and create useful pharmaceutical preparations when deployed with a pharmaceutically acceptable carrier for administration to a host, e.g., man, requiring vasoconstrictive therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.