Bis-carbamylguanidinoazaalkane antimicrobial compounds
US4110328A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Oct 26, 1976 |
| Grant date | Aug 29, 1978 |
| Priority date | — |
| Expiry date | Oct 26, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D243/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Antimicrobial compounds are disclosed having the formula: EQU Z--B--Y--B--Z .rHA wherein B is carbamylguanidino or thiocarbamylguanidino, Y is a nitrogen-containing alkylene group having the structural formula: ##STR1## WHEREIN: N = 2-4 PA0 m = 2-4 PA0 p = 1,2 PA0 q = 2-4 PA0 x = 0-3 PA0 y = 0-2 PA0 x = 0 when y .noteq. 0 and y = 0 when x .noteq. 0, And R is hydrogen or a C.sub.1 -C.sub.8 hydrocarbon radical selected from the group consisting of alkyl, alkenyl, alkynyl, cycloalkyl, and aralkyl radicals, R' and R" are each hydrogen or C.sub.1 -C.sub.4 alkyl and may be the same or different and Z is selected from the group consisting of C.sub.1 -C.sub.12 alkyl, di(C.sub.1 -C.sub.10 alkylamino)-C.sub.10 -C.sub.2 having a total carbon content of C.sub.4 -C.sub.12 ; C.sub.3 -C.sub.12 alkenyl; C.sub.3 -C.sub.12 alkynyl; C.sub.3 -C.sub.12 cycloalkyl, C.sub.4 -C.sub.12 cycloalkylalkyl; C.sub.6 -C.sub.12 cycloalkenyl, C.sub.7 -C.sub.14 cycloalkenylalkyl, C.sub.7 -C.sub.12 polycycloalkyl, C.sub.8 -C.sub.14 polycycloalkylalkyl, C.sub.7 -C.sub.12 polycycloalkenyl, C.sub.8 -C.sub.14 polycycloalkenylalkyl, C.sub.1 -C.sub.10 alkoxy-C.sub.10 -C.sub.2 alkyl having a total carbon content of C.sub.3 …
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.