Novel immunological adjuvants, process for their production and compositions containing them
US4110434A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 3, 1976 |
| Grant date | Aug 29, 1978 |
| Priority date | — |
| Expiry date | Aug 3, 1996 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/27
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel derivatives with immunological activity are obtained by reacting a hydrosoluble extract of mycobacteria with an aliphatic acid derivative containing 10 to 18 carbon atoms and isolating the resulting product. The hydrosoluble extract of mycobacteria is a tetrasaccharide-heptapeptide or its dimer, trimer or tetramer possibly associated with non-amino reducing sugars. The derivative has the formula: ##STR1## IN WHICH M IS A WHOLE NUMBER COMPRISED BETWEEN 1 AND 4 INCLUSIVE, N IS A WHOLE NUMBER AT LEAST EQUAL TO 1 AND R is an alkyl radical containing 9 to 17 carbon atoms.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.