Patent · US Expired

Novel immunological adjuvants, process for their production and compositions containing them

US4110434A · kind A · utility

5Cited by
5References
18Claims
0Family size

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Key dates

Filing dateAug 3, 1976
Grant dateAug 29, 1978
Priority date
Expiry dateAug 3, 1996

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S930/27
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Novel derivatives with immunological activity are obtained by reacting a hydrosoluble extract of mycobacteria with an aliphatic acid derivative containing 10 to 18 carbon atoms and isolating the resulting product. The hydrosoluble extract of mycobacteria is a tetrasaccharide-heptapeptide or its dimer, trimer or tetramer possibly associated with non-amino reducing sugars. The derivative has the formula: ##STR1## IN WHICH M IS A WHOLE NUMBER COMPRISED BETWEEN 1 AND 4 INCLUSIVE, N IS A WHOLE NUMBER AT LEAST EQUAL TO 1 AND R is an alkyl radical containing 9 to 17 carbon atoms.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.