Antiinflammatory imidazothiazoles and thiazolopyrimidines
US4110451A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 29, 1976 |
| Grant date | Aug 29, 1978 |
| Priority date | — |
| Expiry date | Dec 29, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D235/28
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Certain imidazothiazoles and thiazolopyrimidines have been found to prevent and inhibit the formation of granuloma tissue in animals. This result is accomplished by administering to the animal subject a therapeutically effective amount of a compound having the formula: ##STR1## wherein R is hydrogen or methyl, R' is hydrogen, lower alkyl or thioalkyl, carboxy methyl, or phenyl; R" is lower alkyl, 2-benzofuranyl, naphthyl, phenyl, or mono- or disubstituted phenyl. The hydrated precursors of certain of these compounds as well as the acid addition and quaternary salts of both the compounds and their hydrated precursors may be employed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.