Method for removal of thiol-protecting groups
US4111924A · kind A · utility
4Cited by
2References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 13, 1977 |
| Grant date | Sep 5, 1978 |
| Priority date | — |
| Expiry date | Jun 13, 1997 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/16
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A novel method for removal of protective group(s) from an amino acid or peptide having thiol group(s) protected with p-methoxybenzyl, 1-adamantyl or t-butyl group by treating the protected amino acid or peptide with the mercuric salt of acetic acid or halogenoacetic acid, the removal being effected selectively and very smoothly in a good yield under extremely mild conditions without giving any undesirable influence upon other functional or protective group(s).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.