Interface for use in a combined liquid chromatography - mass spectrometry system
US4112297A · kind A · utility
39Cited by
1References
7Claims
0Family size
Assignee
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Key dates
| Filing date | Jun 30, 1977 |
| Grant date | Sep 5, 1978 |
| Priority date | — |
| Expiry date | Jun 30, 1997 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N1/22
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A new interface is interposed between a liquid chromatograph and a mass spectrometer, and it consists of a nebulizer, an evaporator and a cooler. An effluent from the liquid chromatograph is nebulized by the nebulizer. The nebulized effluent is heated by the evaporator, and has only its solvent evaporated. A mixed fluid which consists of the evaporated solvent and the nebulized sample is guided to the cooler, and is cooled therein. At this time, the evaporated solvent is condensed again and is separated from the nebulized sample as a liquid. The nebulized sample left behind is guided to an ion source of the mass spectrometer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.