Prostaglandin derivatives and process for preparing the same
US4115401A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 31, 1977 |
| Grant date | Sep 19, 1978 |
| Priority date | — |
| Expiry date | Mar 31, 1997 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/4006
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Prostaglandin derivatives corresponding to the general formula: ##STR1## wherein R.sub.1 represents hydrogen, methyl or ethyl, R.sub.2, R.sub.3 and R.sub.4, which are the same or different, each represent hydrogen or methyl and R is selected from the groups consisting of: ##STR2## in which R.sub.5 represents hydrogen, methyl or ethyl, R.sub.6 represents methyl, ethyl or acetyl and R.sub.7 and R.sub.8, when they are different, each represent hydrogen or a branched- or straight-chain alkyl group having from 1 to 7 carbon atoms or R.sub.7 and R.sub.8, when they are identical, each represent hydrogen or a straight-chain alkyl group having from 1 to 3 carbon atoms with the provisos that: PA0 When both R.sub.7 and R.sub.8 represent hydrogen, R.sub.5 is methyl or ethyl, PA0 When R.sub.5 represents methyl and R.sub.2, R.sub.3, R.sub.4, R.sub.7 and R.sub.8 all represent hydrogen then R.sub.1 is ethyl, The said prostaglandin derivatives being in the form of a mixture of isomers or of an individual isomer. They are useful in the treatment of pathological states which affect the respiratory system.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.