Carbamylguanidine antimicrobial compounds
US4115448A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jan 7, 1977 |
| Grant date | Sep 19, 1978 |
| Priority date | — |
| Expiry date | Jan 7, 1997 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C279/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Antimicrobial compounds are disclosed having the formula: EQU Z--B--Y--B--Z .nHA wherein B is carbamylguanidino, or thiocarbamylguanidino, Y is a bivalent organic radical selected from the group consisting of C.sub.2 -C.sub.12 alkylene, C.sub.5 -C.sub.12 cycloalkylene, C.sub.5 -C.sub.12 cycloalkylenebis(loweralkyl), C.sub.6 -C.sub.12 arylene and loweralkylarylene, C.sub.7 -C.sub.12 aryleneloweralkyl, and C.sub.8 -C.sub.12 arylenebis(loweralkyl) and Z is selected from the group consistng of C.sub.1 -C.sub.2 alkyl; C.sub.4 -C.sub.12 dialkylaminoalkyl; C.sub.3 -C.sub.12 alkenyl; C.sub.3 -C.sub.12 alkynyl; C.sub.3 -C.sub.12 cycloalkyl, C.sub.4 -C.sub.12 cycloalkylalkyl; C.sub.1 -C.sub.10 alkoxy C.sub.10 -C.sub.2 alkyl having a total carbon content of C.sub.3 -C.sub.14 ; C.sub.1 -C.sub.10 alkythio C.sub.10 -C.sub.2 alkyl having a total carbon content of C.sub.3 -C.sub.14 ; phenoxy C.sub.2 -C.sub.6 alkyl; phenylthio C.sub.2 -C.sub.6 alkyl; C.sub.6 -C.sub.14 aryl; C.sub.7 -C.sub.14 aralkyl and arylcycloalkyl; and C.sub.6 -C.sub.14 aryl and aralkyl substituted with one or more radicals selected from the group consisting of loweralkyl, trifluoromethyl, loweralkoxy, trifluoromethoxy, phenoxy…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.