Novel 5,6,7,8-tetrahydro-5-quinolines and their use as anti-inflammatory agents
US4117135A · kind A · utility
1Cited by
4References
31Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 8, 1975 |
| Grant date | Sep 26, 1978 |
| Priority date | — |
| Expiry date | Oct 8, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Pyridine derivatives of the formula ##STR1## wherein R.sub.1 is an alkyl, aliphatic, a cycloalkyl, or a substituted or unsubstituted hydrocarbon aryl and the substituent is halogen, alkoxy or methylenedioxy; R.sub.2 is H or Cl; X is CN, 5-tetrazolyl, or COOH or a carboxylic acid derivative; Y is H, OH, OCOR.sub.7, NH.sub.2, NHCOR.sub.8, R.sub.9, COOH or COOR.sub.10 and R.sub.7, R.sub.8, R.sub.9 and R.sub.10 are alkyl groups of 1-10 carbon atoms; A is methylene or a carbon-to-carbon bond; and R.sub.3 and R.sub.4 are each H or alkyl groups of 1-4 carbon atoms, are useful as anti-inflammatory agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.