Preparation of sucrose 6,6'-dichloro hexa-acetate
US4117224A · kind A · utility
12Cited by
4References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 11, 1975 |
| Grant date | Sep 26, 1978 |
| Priority date | — |
| Expiry date | Dec 11, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H13/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
6,6'-Dichloro-6,6'-dideoxysucrose is obtained directly in high yield by reacting sucrose with methanesulphonyl chloride in N,N-dimethylformamide. 1',6,6'-Trichloro-1',6,6'-trideoxysucrose is obtained as a by-product and its formation can be suppressed by starting the reaction at -40.degree. C to -15.degree. C. The dichlorodideoxy and trichloro-trideoxy compounds, which are useful as intermediates for preparing other sucrose derivates, are most conveniently isolated from the reaction mixture in the form of their hexa-acetate and penta-acetate respectively, which are then deacetylated to give the free compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.