Production of N-(substituted) morpholine
US4117227A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jun 2, 1975 |
| Grant date | Sep 26, 1978 |
| Priority date | — |
| Expiry date | Jun 2, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G18/2018
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
An improved process is disclosed for selectively producing an N-(substituted) morpholine compound from the corresponding N-(substituted) diethanolamine compound. The improved process includes contacting the N-(substituted) diethanolamine compound with a catalytically effective amount of a silica-alumina or certain phosphorus-containing substances at temperatures of from about 190.degree. C to about 260.degree. C under a pressure sufficient to maintain the mixture substantially in liquid phase and recovering from the reaction mixture the formed N-(substituted) morpholine. According to a preferred embodiment, triethanolamine is heated in the presence of a catalytically effective amount of a silica-alumina catalyst having an aluminum content of from about 5 to about 50 wt. % at temperatures of from about 240.degree. C to about 260.degree. C in liquid phase to selectively produce the corresponding N-(hydroxyethyl)morpholine (HEM).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.