Patent · US Expired

Decapeptide analogs of somatostatin

US4118380A · kind A · utility

4Cited by
1References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 25, 1977
Grant dateOct 3, 1978
Priority date
Expiry dateJul 25, 1997

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S930/16
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compounds of the formula 1 or 1a ##STR1## EQU HSCH.sub.2 CH.sub.2 CO-A-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-NHCH.sub.2 CH.sub.2 SH (1a) in which A is Gly-Asn or Lys-Gly, or therapeutically acceptable salts thereof are disclosed. The compounds of formulae 1 and 1a are useful for the management of diabetes and the treatment of acromegaly in mammals. Compositions and methods for their use also are disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.