Catalyzed production of phosphorous and phosphonous acid ester chlorides

US4118435A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Roland Kleinstuck · Bensberg, DE
• Hans-Dieter Block · Cologne, DE

Key dates

• Filing date: Jul 27, 1977
• Grant date: Oct 3, 1978
• Expiry date: Jul 27, 1997

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F9/425
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

In the production of phosphorous or phosphonous acid ester chlorides of the formula EQU R.sub.m (R'O).sub.n PCl.sub.3-m-n wherein PA1 R and R' are various organic radicals, PA1 m = 0 or 1, PA1 n = 1 or 2, and PA1 m+n = 1 or 2, By reacting a trialkylphosphite, a triarylphosphite, a dialkylchlorophosphite or a diarylchlorophosphite with phosphorustrichloride, phosphorous acid alkyl ester dichloride, phosphorous acid aryl ester dichloride, or by reacting a dialkyl-phosphonite with dichlorophosphonite, at a temperature between about -10.degree. C and 120.degree. C, the improvement which comprises effecting the reaction in the presence of a catalytic quantity of a compound of at least one of 3- and 5-valent phosphorus, e.g. a phosphine, phosphine oxide, phosphine sulfide, halogen-phosphorane or phosphoric acid-tris-amide. A small amount of an alcohol or dialkalphosphite increases the yield.