Anti-anxiety and anti-parkinsonian 1-aminoalkyl-2-endo-chloro-7,7-dimethylnorbornanes

US4118499A · kind A · utility

Assignee

• Glaxo Laboratories Limited

Inventors

• Leslie Stephenson
• Colin M. Smith · Forbes, AU

Key dates

• Filing date: Oct 8, 1976
• Grant date: Oct 3, 1978
• Expiry date: Oct 8, 1996

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D295/084
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

1-Aminoethyl, 1-aminopropyl and 1-aminobutyl derivatives of 7,7-dimethylnorbornane are described. The amino groups are optionally substituted, for example by alkyl groups, or may be saturated heterocyclic amino groups. The alkylene group at the 1-position can also be substituted, and the 2-position can be substituted by chlorine. The compounds have CNS activity.