Patent · US Expired

Organic compounds

US4120852A · kind A · utility

19Cited by
1References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 7, 1975
Grant dateOct 17, 1978
Priority date
Expiry dateMay 7, 1995

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

This invention provides new compounds of formula I, ##STR1## wherein X is H-Ala, D-Ala, .beta.-Ala, propionyl or Ac-Ala (wherein Ac is pharmaceutically acceptable acyl), PA1 Y is hydrogen or a direct bond between the sulphur atoms in positions 3 and 14, and PA1 Z is the radical --COOH, --COOR.sub.1 (wherein R.sub.1 is lower alkyl), ##STR2## (wherein R.sub.2 and R.sub.3 independently are hydrogen or lower alkyl) or --CH.sub.2 OH, PA1 with the proviso that X is other than H-Ala, when Z is COOH. useful as agents for the treatment of Diabetes Mellitus, acromegaly and angiopathy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.