Therapeutic agents
US4120960A · kind A · utility
1Cited by
4References
29Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 1, 1977 |
| Grant date | Oct 17, 1978 |
| Priority date | — |
| Expiry date | Aug 1, 1997 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D403/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Therapeutic activity, and in particular the ability to induce diuresis or saluresis, has been discovered in 4-hydroxy- or 4-mercapto-2-aryl-1,2-dihydrophthalazine-1-acetic acids, the tautomers of these namely 4-oxo or thio-2-aryl-1,2-tetrahydrophthalazine-1-acetic acids, and in the ester and alcohol derivatives of the acids, and in the acyl derivatives of the 4-hydroxy or mercapto compounds and in the 3-alkyl derivatives of the 4-oxo or thio compounds. Therapeutic compositions and methods using the compounds are described, as also are novel compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.