Fused pyrimidin-4(3H)-ones as antiallergy agents

US4120962A · kind A · utility

Assignee

• PFIZER INC. · US

Inventors

• Thomas H. Althuis · Groton, US
• Leonard J. Czuba · New London, US
• Hans-Jurgen E. Hess · Old Lyme, US
• Saul B. Kadin · New London, US

Key dates

• Filing date: Apr 11, 1977
• Grant date: Oct 17, 1978
• Expiry date: Apr 11, 1997

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D265/26
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Fused heterocyclic ring systems in which a quinoline or a pyridine component is "fused" to a pyrimidine having a 2-methyl, 2-ethyl, or 2-acetyl group and a 4-keto group, and to similar ring systems in which a quinoline, a naphthalene or a pyridine component is "fused" to a pyrimidine having a 2-carboxy group and a 4-keto group, derivatives, and pharmaceutically-acceptable cationic salts thereof, and their use as antiallergy agents, and intermediates therefor.