Amides of pyrrolidinoethylamine which can be used in treatment of coughs
US4122199A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 16, 1976 |
| Grant date | Oct 24, 1978 |
| Priority date | — |
| Expiry date | Aug 16, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D311/84
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
New chemical compounds, which are pyrrolidinoethylamine amides, in the form of free bases and salts thereof, which are useful as antitussives, pharmaceutical compositions thereof, and method of treating therewith. In the form of their salts, the compounds have the formula: ##STR1## wherein ##STR2## is an acyl radical of a phenylacetic, 60 -phenyl-.alpha.-(1 to 5 C atoms) acetic, (1 to 5 C atoms) diphenylacetic, benzilic, diphenyl-.alpha.-chloroacetic, .alpha.-lower-alkoxy-.alpha.,.alpha.-diphenylacetic, 3-coumarincarboxylic, 9-xanthenecarboxylic, phenoxyacetic, phenoxyisobutyric, halophenoxyisobutyric, or 9-flourene carboxylic acid, and wherein R'H represents an inorganic or organic acid. Medicaments containing these active principles may be used, inter alia, in the treatment of coughs and respiratory complaints.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.