Enlarged-hetero-ring prostacyclin analogs
US4123441A · kind A · utility
57Cited by
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22Claims
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Assignee
Inventor
Key dates
| Filing date | Jul 28, 1977 |
| Grant date | Oct 31, 1978 |
| Priority date | — |
| Expiry date | Jul 28, 1997 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D311/94
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Prostaglandin (PG.sub.1) derivatives having (1) a 5-keto feature, for example ##STR1## or (2) a 9-deoxy-5,9-epoxy feature together with a 4-halo or 5-hydroxy feature, for example ##STR2## or a 4,5-didehydro feature, for example in an enol ether of the formula ##STR3## said derivatives having pharmacological activity. Processes for preparing them and the appropriate intermediates are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.