DI-Tham salt of 10-cl,1,4,6,9 tetrahydro-5-methyl 4,6 dioxopyrido[3,2-g]quinoline-2,8-dicarboxylate
US4126617A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 5, 1976 |
| Grant date | Nov 21, 1978 |
| Priority date | — |
| Expiry date | Aug 5, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C205/57
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel chemical compounds of the formula: ##STR1## wherein R is selected from the group consisting of hydrogen, alkyl from one to three carbon atoms, inclusive, phenyl, alkali metal, or an amine cation; PA0 X and Y can be the same or different and are selected from the group consisting of hydrogen, alkyl or from one to six carbon atoms, inclusive, cycloalkyl of 5 or 6 carbon atoms, inclusive, phenyl, hydroxyl, alkoxy having from one to three carbon atoms, inclusive, halogen, trifluoromethyl, cyano, carboxyamide and ##STR2## where Q is selected from the group consisting of hydrogen, alkyl from one to three carbon atoms, inclusive, alkali metal, and an amine cation, with the proviso that where PA0 R is hydrogen, alkali metal or an amine cation, then Q is the same as R, and where PA0 R is phenyl or alkyl from one to three carbon atoms, then Q is phenyl or alkyl from one to three carbon atoms; and PA0 Z is selected from the group consisting of hydrogen, alkyl from one to three carbon atoms, inclusive, and phenyl. PA0 The compounds are formulated with pharmaceutical carriers for oral or parenteral administration, with insufflation being the preferred method. The compositions are useful i…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.