Halohydrin thioethers and method of preparation
US4126746A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 9, 1971 |
| Grant date | Nov 21, 1978 |
| Priority date | — |
| Expiry date | Aug 9, 1991 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D251/34
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of the structure R(SCH.sub.2 CHOHCH.sub.2 X).sub.n when n = 1 to 4 and R is a hydrocarbon, ether, ester, acetal, hydroxy aliphatic, hydroxy aromatic, imide or amide group or halogenated derivatives thereof are prepared by reacting 1-halo-3-mercapto-2-propanol with an aliphatically unsaturated compound using free radical initiators as catalysts. The compounds in which R is an unsaturated aliphatic hydrocarbon group of 2 to 24 carbon atoms, or an unsaturated cycloaliphatic group, and those in which the aliphatic or cycloaliphatic group is connected to two or more --S--CH.sub.2 CHOHCHCl groups, and compounds where R is an alkylene substituted aromatic group and hydroxy, thioalkyl, alkoxy, aryloxy, ester, carbamidoalkyl and sulfamidoalkyl, halogenated derivatives of said groups are new compounds. The thioether halohydrins can be converted to epoxides. The process utilizing a radioactive energy source as a catalyst is new.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.