Patent · US Expired

Aminomethanobenzazocine process

US4127577A · kind A · utility

2Cited by
5References
1Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 20, 1976
Grant dateNov 28, 1978
Priority date—
Expiry dateSep 20, 1996

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D221/22
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

N-Alkylated-8-aminated-2,6-methano-3-benzazocines, useful as strong analgesics, are prepared by one route comprising reduction of 8-nitro intermediates or by another route comprising Birch type reduction of 8-methoxy intermediates followed by dehydration-rearrangement of the oximes of the resulting 8-oxo intermediates.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.