Process for preparing phenylacetic acid
US4128572A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 18, 1978 |
| Grant date | Dec 5, 1978 |
| Priority date | — |
| Expiry date | Jan 18, 1998 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C51/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to a process for preparing phenylacetic acid. In particular, the present invention relates to a catalytic process for the synthesis of the alkaline salts of phenylacetic acid by carbonylation of benzyl halides in a diphase system in the presence of cobalt carbonyl complexes. More particularly, the present invention relates to a process for preparing alkaline salts of phenylacetic acid by reacting a benzyl halide selected from chloride and bromide with carbon monoxide in the presence of a catalyst consisting in a salt of cobalt hydrocarbonyl, characterized in that the reaction is conducted in an aqueous/organic diphase system consisting of (a) an aqueous solution of an inorganic alkaline base, and (b) the benzyl halide in an organic solvent, in the presence of a catalyst system composed by a quaternary alkylammonium salt and by a cobalt hydrocarbonyl salt, at atmospheric pressure and at a temperature ranging from 20.degree. to 70.degree. C about.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.