Styrylamidines
US4130663A · kind A · utility
48Cited by
1References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 10, 1978 |
| Grant date | Dec 19, 1978 |
| Priority date | — |
| Expiry date | Apr 10, 1998 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/155
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Styrylamidines are prepared by treating styrylsulfonylamidines with base. The styrylamidines are effective in the prevention of aggregation of blood platelets and as analgesics. Compounds of the invention are also useful as anticonvulsants, diuretics, and antihypertensive agents. The styrylsulfonylamidines of the invention which serve as precursors to the styrylamidines also have analgesic properties. Illustrative of the styrylamidines of the present invention are 4-amino-N-(4-aminostyryl)benzamidine and N-(3,4-dichlorostyryl)acetamidine. An example of a styrylsulfonylamidine is N-(styrylsulfonyl)acetamidine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.