Preparation of new isobutylramide derivatives
US4131617A · kind A · utility
11Cited by
1References
2Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Mar 17, 1977 |
| Grant date | Dec 26, 1978 |
| Priority date | — |
| Expiry date | Mar 17, 1997 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C255/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for the preparation of an isobutyramide is disclosed. A sodium phenolate is prepared by reacting sodium with a phenol in ethanol, an excess of toluene is added to the solution to form an ethanol/toluene azeotrope which azeotrope is then removed by distillation whereafter a N-cyanoalkyl .alpha.-bromo-isobutyramide is added, the mixture is refluxed for a period of 6-15 hours after which water is added to form a precipitate which is then removed from the reaction mixture.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.