Polymeric carrier for a controlled synthesis of peptides and the method of its preparation
US4133942A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 30, 1977 |
| Grant date | Jan 9, 1979 |
| Priority date | — |
| Expiry date | Nov 30, 1997 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08F8/24
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
An acrylic polymer gel suitable for use as a carrier in the controlled synthesis of polypeptides is provided. The polymer comprises a diazotized terpolymer of the condensation product of a monomer selected from the group consisting of hydroxyalkyl acrylates and hydroxyalkyl methacrylates, a polyfunctional cross-linking monomer selected from the group consisting of alkylene diacrylates, alkylene dimethacrylates, polyacrylates and polymethacrylates of polyalcohols, alkylene bisacrylamides and divinylbenzene, and an aromatic ring-containing compound selected from the group consisting of aromatic acids and their anhydrides and chlorides, aromatic isocyanates, halogenophenylsilanes, and aromatic epoxy compounds. The condensate has its aromatic rings chlormethylated. The first monomer and the polyfunctional cross-linking monomer are copolymerized and the resultant copolymer is condensed with said compounds which contain an aromatic ring.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.