Antipsychotic 1-[4,4-Bis(4-fluorophenyl) butyl]-4-phenoxy-1,2,3,6-tetrahydropyridines
US4134982A · kind A · utility
6Cited by
2References
36Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 26, 1977 |
| Grant date | Jan 16, 1979 |
| Priority date | — |
| Expiry date | Sep 26, 1997 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D213/68
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
1-[4,4-Bis(4-fluorophenyl)butyl]-4-phenoxy-1,2,3,6-tetrahydropyridines and related piperidines are disclosed in the present invention. These compounds have the structural formulas: ##STR1## in which X is hydrogen, halogen, dihalogen, trifluoromethyl, lower alkoxy, nitro, amino, cyano, lower alkyl, aryl or substituted aryl. Also included are the corresponding non-toxic, pharmaceutically acceptable acid addition salts, and the N-oxides of compounds of the formulas I and II. The above compounds are useful in the management of manifestations of psychotic disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.