Hypoglycaemically active 2-(phenylalkyl- or -alkenyl hydrazono)-propionic acid derivatives

US4136196A · kind A · utility

Assignee

• Boehringer Mannheim GmbH · DE

Inventors

• Rainer Haeckel
• Michael Oellerich · Hannover, DE
• Ruth Heerdt · Mannheim, DE
• Manfred Hubner · Ludwigshafen am Rhein, DE
• Hans-Frieder Kuhnle · Weinheim, DE

Key dates

• Filing date: Sep 22, 1977
• Grant date: Jan 23, 1979
• Expiry date: Sep 22, 1997

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P3/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A 2-hydrazono-propionic acid derivative of the formula ##STR1## wherein R.sub.1 and R.sub.2, each independently is hydrogen, halogen, trifluoromethyl, alkyl, hydroxyl, acyloxy or alkoxy or together are methylenedioxy, and PA1 X is an aliphatic hydrocarbon radical containing 2-4 carbon atoms and is optionally substituted by an alkyl radical in the .beta.- or .gamma.-position to the nitrogen atom, Or a physiologically compatible salt, ester or amide thereof, which exhibit hypoglycaemically activity.