Glycoside-ether-ester compounds
US4137401A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 21, 1976 |
| Grant date | Jan 30, 1979 |
| Priority date | — |
| Expiry date | Jun 21, 1996 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/807
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Carbohydrate antigenic determinants containing a glycosidically linked bridging arm are synthesized and coupled to carrier molecules to form artificial antigens, and to solid supports to form immunoabsorbants. These artificial antigens are used to detect antibodies to the carbohydrate haptens, and to raise antisera specific for the carbohydrate antigenic determinants. The immunoabsorbants are used to purify or remove antibodies to the carbohydrate haptens. Specific examples are given to the synthesis of the Lewis-a, Lewis-b, B, and H(O) blood group antigens; to the preparation of antisera to these artificial antigens, and to the preparation of immunoabsorbants specific for antibodies to these antigens.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.