Addition copolymers of lactide and glycolide and method of preparation
US4137921A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 24, 1977 |
| Grant date | Feb 6, 1979 |
| Priority date | — |
| Expiry date | Jun 24, 1997 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G63/08
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Relatively high molecular weight, fiber-forming, crystalline copolymers of lactide and glycolide are prepared in a two-stage polymerization process. In the first stage there is prepared a random copolymer of a major proportion of an optically active lactide with a minor proportion of glycolide or d,l-lactide. In the second stage, a major amount of glycolide and a minor amount of lactide monomers are admixed with the copolymer of the first stage and the polymerization resumed until there is obtained a high molecular weight addition copolymer of lactide and glycolide containing from about 50 to 75 wt percent of units derived from glycolide. The polymer is fiber-forming and useful in the preparation of absorbable surgical sutures.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.