Preparation of small bio-compatible microspheres
US4138383A · kind A · utility
117Cited by
6References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 24, 1975 |
| Grant date | Feb 6, 1979 |
| Priority date | — |
| Expiry date | Nov 24, 1995 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S524/90
- WIPO fieldMacromolecular chemistry, polymers
- WIPO sectorChemistry
Abstract
Small, round, bio-compatible microspheres capable of covalently bonding proteins and having a uniform diameter below about 3500 A are prepared by substantially instantaneously initiating polymerization of an aqueous emulsion containing no more than 35% total monomer including an acrylic monomer substituted with a covalently bondable group such a hydroxyl, amino or carboxyl and a minor amount of a cross-linking agent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.