Process for the preparation of immunopotentiating agents from components of yeast cell wall material

US4138479A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Ernst Truscheit · Häger, DE
• Robert Bierling · Wuppertal, DE
• Horst D. Schlumberger · Wuppertal, DE
• Herbert F. Oettgen · New Canaan, US

Key dates

• Filing date: Sep 12, 1977
• Grant date: Feb 6, 1979
• Expiry date: Sep 12, 1997

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12R2001/865
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A water soluble immunopotentiating agent is derived from yeast cell wall material, including mechanically disrupted yeast cell walls, proteolyzed yeast cell wall material and carbohydrate-protein complexes found in yeast cell wall material, through extraction with a water-phenol mixture. The water soluble agent is isolated from the water phase and can be further purified, as through dialysis, to remover low molecular weight components.