1,2-Dithiole derivatives
US4138487A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 28, 1977 |
| Grant date | Feb 6, 1979 |
| Priority date | — |
| Expiry date | Nov 28, 1997 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D241/24
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
1,2-Dithiole derivatives of the formula: ##STR1## wherein Het represents an aromatic heterocyclic radical with six atoms in the ring two of which are nitrogen atoms, the heterocyclic radical optionally carrying a single substituent selected from halogen, alkyl, alkoxy, mercapto, alkylthio, dialkylamino, pyrrolidin-1-yl, piperidino, morpholino and 4-alkylpiperazin-1-yl, and R represents halogen, alkyl (optionally substituted by alkoxycarbonyl), carboxy, alkoxycarbonyl, carbamoyl, N-alkylcarbamoyl or a group R.sub.1 --CH(OH)-- in which R.sub.1 represents hydrogen or alkyl, the said alkyl, alkoxy and alkylthio radicals or alkyl or alkoxy moieties containing 1 to 4 carbon atoms except in the case of R.sub.1 which contains 1 to 3 carbon atoms when an alkyl radical, are new compounds useful in the treatment of bilharziasis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.