Patent · US Expired

N-(4-substituted-3,5-dichloro-phenyl)-piperazines

US4139621A · kind A · utility

3Cited by
2References
25Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 5, 1977
Grant dateFeb 13, 1979
Priority date
Expiry dateDec 5, 1997

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D295/205
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

1-(3,5-Dichlorophenyl)piperazines bearing a fluoro, chloro, methyl, nitro, hydroxy, methoxy, cyano, amino, methylamino or dimethylamino substituent in the 4-position of the phenyl ring and being further optionally substituted in the 4-position of the piperazine ring by tetrahydropyranyl, alkyl, formyl, carboxy, alkanoyl or carboalkoxy, and the acid addition salts thereof, are tranquilizers. A typical embodiment is 1-(3,4,5-trichlorophenyl)piperazine hydrochloride.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.