Patent · US Expired

2,9-Dioxatricyclo[4,3,1,0.sup.3,7 ]decane derivatives, processes for their preparation and pharmaceutical compositions thereof

US4141988A · kind A · utility

2Cited by

2References

25Claims

0Family size

Assignee

Kali-Chemie Pharma GmbH · DE

Inventors

Peter W. Thies · Hannover, DE
Samuel David · Dorval, CA
Hartmut Hauth · Riehen, CH
Dietmar Roemer · Pfullendorf, DE

Key dates

Filing date	Feb 2, 1978
Grant date	Feb 27, 1979
Priority date	—
Expiry date	Feb 2, 1998

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P25/04
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

4-amino-3-methyl-2,9-dioxatricyclo[4,3,1,0.sup.3,7 ]decane derivatives are disclosed which exhibit analgesic properties, and which have the formula (I) ##STR1## wherein ONE OF R.sub.1 and R.sub.2 represents hydrogen and the other represents an amino group which is substituted by an arylalkyl group or an arylalkenyl group, PA1 One of R.sub.3 and R.sub.4 represents hydrogen and the other represents alkoxy, and PA1 Y and y' each represent hydrogen or jointly form a bond, and pharmaceutically acceptable acid addition salts thereof, as well as pharmaceutical formulations thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.