Patent · US Expired

Process for the purification of clavulanic acid

US4144242A · kind A · utility

11Cited by
0References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 16, 1976
Grant dateMar 13, 1979
Priority date
Expiry dateDec 16, 1996

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12P17/188
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The invention provides the compound (2R,5R,Z)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo-[3,2,0]-heptane -2-carboxylic acid and its salts in purified form and pharmaceutical compositions containing them and a process for the purification of such compounds by conversion in aqueous media to the lithium salt of the above acid and precipitation thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.